XB-FEAT-985439

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cirsr

This is the community wiki page for the gene cirsr please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.


nomenclature updates

30APR2026

Xenopus gene names changed from cir1,corepressor interacting with RBPJ, 1 to cirsr, corepressor of RBPJ and splicing regulator .


summary for human CIRSR from NCBI

Enables histone deacetylase binding activity; protein kinase binding activity; and transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in centrosome and nuclear speck. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]