XB-FEAT-5899960

hemk2

This is the Xenopus community wiki page for the gene hemk2, please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08/15/2017 Human name has changed for Entrez Gene: 29104. From N-6 adenine-specific DNA methyltransferase 1 (putative) to N-6 adenine-specific DNA methyltransferase 1

02JUL2025

HUMAN GENEID:6021 NAME CHANED TO HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine, FROM N6AMT1, N-6 adenine-specific DNA methyltransferase 1. Approved 2025-02-07

XENOPUS GENE NAME CHANGED TO FOLLOW HUMAN NOMENCLATURE.

summary from NCBI for the human ortholog

This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Mar 2023]