Echinomycin
Jump to navigation
Jump to search
- http://www.xenbase.org/literature/article.do?method=display&articleId=4170
- https://pubchem.ncbi.nlm.nih.gov/compound/3197
Echinomycin is a polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis. (NCI04)