XB-FEAT-29089782

or6n2

This is the community wiki page for the gene or6n2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature updates

14MAY2026

Xenopus gene name was changed from or6n3, olfactory receptor family 6 subfamily N member 3 to or6n2, olfactory receptor family 6 subfamily N member 2 to match the human ortholog as identified by NCBI.

Note tha Olfactory Receptors are short 1 exon genes that evolve quickly, and generally are impossible to classify by sequence similarity or synteny. Xenopus ORs have a unique naming system, however, or6n3 seems very simialr to the Human OR6N3, so we are happy to give it the same symbol, although it is probably NOT a true ortholog (ie with shared inherited ancestry).

CJZ

summary from NCBI for human OR6N2

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]